Soulager le blues d’automne avec des microdoses de psilocybine.
Lindsey Bartlett Contributeur
Je couvre l’industrie du cannabis, les psychédéliques, la culture et l’innovation.
5 juil. 2022,01:39pm EDT
Une nouvelle étude publiée dans Nature : Scientific Reports a observé des bénéfices significatifs sur l’humeur et la santé mentale après un mois de microdosage de champignons psilocybines.
Les microdoseurs de champignons ont constaté de plus grandes améliorations dans les domaines de la dépression, de l’anxiété et du stress du DASS. L’étude indique qu’elle n’a trouvé aucune différence dans ces résultats entre les sexes, mais elle a constaté que l’efficacité cognitive de la microdose était plus performante chez les personnes âgées de moins de 55 ans.
L’étude a porté sur 1133 personnes sur une période de deux ans. Tous les sujets étaient âgés de plus de 18 ans, capables de lire en anglais et avaient accès à un appareil iPhone iOS où les participants enregistraient leurs résultats. Scientific Reports est une revue scientifique à accès libre, évaluée par des pairs et publiée en ligne par Nature Portfolio.
L’étude a été menée par une équipe d’experts dans les domaines de la psychologie et de la mycologie : Joseph M. Rootman, département de psychologie de l’université de Colombie-Britannique, Kelowna, BC, Canada ; Maggie Kiraga, employée de Quantified Citizen Technologies. Pamela Kryskow, membre du conseil consultatif clinique de Numinus Wellness, cofondatrice de MycoMedica Life Sciences et membre du conseil consultatif scientifique et médical ; Kalin Harvey ; Paul Stamets, qui a fondé Fungi Perfecti, LLC ; Eesmyal Santos-Brault ; Kim P. C. Kuypers ; et Zach Walsh, membre du conseil consultatif de l’Association multidisciplinaire pour les études psychédéliques (MAPS) Canada et de MycoMedica Life Sciences.
“Cette étude est une extension de notre manuscrit précédent publié dans la même revue, et nous avons d’autres publications en préparation qui sont basées sur cette même étude”, déclare Joseph Rootman, chercheur au département de psychologie de l’université de Colombie-Britannique. Il ajoute que l’équipe prévoit de poursuivre cette ligne de recherche et de développer ces résultats à l’avenir. “Notre équipe a également travaillé dur pour développer la prochaine version de l’étude qui sera utilisée pour générer des résultats liés au microdosage psychédélique pour les années à venir.”
Il n’y a pas un type spécifique de champignon, ou de souche, que l’étude a utilisé parce qu’elle était “observationnelle par nature”, dit Rootman. Les chercheurs n’ont pas fourni de champignons à psilocybine aux participants, mais ont observé et enregistré les expériences des participants alors qu’ils s’engageaient dans leur propre “pratique du microdosage”.
“Dans cette version initiale de l’étude, nous n’avons pas demandé aux participants de préciser la variété de champignon qu’ils utilisaient. Nous avons toutefois recueilli des données sur une pratique appelée “stacking”, qui consiste à combiner des champignons psilocybines avec d’autres substances non psychédéliques telles que les champignons crin de lion ou le chocolat”, explique M. Rootman. “Notre première étude a noté qu’environ la moitié des microdoseurs de notre échantillon empilaient avec une grande variété de substances, tandis que notre étude plus récente a étendu ces résultats en notant des améliorations associées de la capacité psychomotrice chez les microdoseurs empilant par rapport à leurs pairs non empilants ou non microdoseurs.”
Quelle est donc la quantité exacte d’une microdose de psilocybine ? L’équipe s’est tournée vers les précédents. “Sur la base d’études antérieures sur le microdosage de psilocybine, nous avons classé les réponses des participants sur le dosage de la psilocybine en microdoses faibles, moyennes et élevées correspondant respectivement à ≤ .1 gramme de champignon séché, 0,1-0,3 gramme de champignon séché, ≥ 0,3 gramme de champignon séché”, explique Rootman. La plupart des participants ont atterri quelque part dans la fourchette intermédiaire de 0,1 à 0,3 gramme de psilocybine. “Nous avons constaté qu’environ 10 % de notre échantillon de microdosage dans cette étude ont déclaré des doses élevées, 72,6 % ont déclaré des doses moyennes et 16,8 % ont déclaré des doses faibles.”
Ces résultats rejoignent les rangs de nombreuses études universitaires légitimes et évaluées par des pairs qui considèrent la psilocybine comme un traitement prometteur de la dépression. Le Journal of Psychopharmacology a publié plus tôt cette année un suivi de cette étude largement médiatisée de la Johns Hopkins Medicine, qui a révélé que la psilocybine peut continuer à aider les personnes souffrant de dépression jusqu’à un an plus tard.
Lindsey Carmela Bartlett est une auteure, photographe et rédactrice de médias sociaux qui documente l’évolution de l’industrie du cannabis depuis dix ans. Née à Denver, dans le Colorado, elle réside aujourd’hui à Long Beach, en Californie. Au cours de sa carrière, elle a travaillé au Denver Post et à The Cannabist, la première publication sur le cannabis fondée par un quotidien lauréat du prix Pulitzer. Ses reportages ont ensuite été axés sur l’industrie au Marijuana Business Daily et au Hemp Industry Daily, où Mme Bartlett a assuré la couverture des médias sociaux pour la MJBizCon, la plus grande série de conférences sur le commerce du cannabis au monde. Elle a assumé des rôles de rédaction, de médias sociaux et d’édition pour Forbes, Insider, Weedmaps, Green Entrepreneur, Westword, Marijuana Moment, MJBizDaily, Leafly et Merry Jane.
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28 April 2026 at 17h04
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12 May 2026 at 9h08
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6 July 2026 at 11h20
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14 July 2026 at 3h51
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21 July 2026 at 3h22
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26 July 2026 at 17h02
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7 September 2026 at 10h21
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10 September 2026 at 0h37
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25 September 2026 at 5h45
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